On this page
- What Each SDK Is Actually Doing
- Anthropic: Model Context Protocol + Direct API Orchestration
- OpenAI: Agents SDK with Built-In Primitives
- Where Each One Breaks
- Anthropic's Weak Points
- OpenAI's Weak Points
- How I Actually Pick
- Production Patterns Worth Stealing
- Schema Discipline
- Fail Loudly at the Boundary
- Compaction Is Not Optional
- Separate Orchestration from Execution
- The Actual Answer
Anthropic Agent SDK vs OpenAI Agents SDK: What Actually Matters in Production
Everyone has an opinion on which SDK to build with. Most of those opinions come from benchmarks and demos. This one comes from running a multi-product studio where agents handle research, ops, content pipelines, monitoring, and chunks of infrastructure — and where a wrong call costs real time and real money.
Here's how I actually think about the Anthropic agent SDK versus what OpenAI is shipping, and what that choice looks like when the stakes are real.
---
What Each SDK Is Actually Doing
Anthropic: Model Context Protocol + Direct API Orchestration
Anthropic doesn't have a single branded "agent SDK" the way OpenAI does. What they have is the Claude API, tool use (function calling), and the Model Context Protocol (MCP) — an open standard for connecting models to external context sources and tools.
MCP is the interesting piece. Instead of wiring tools directly into your agent loop, you define MCP servers — discrete, composable context providers that your agent can call. The agent stays clean. The integrations live in their own containers. Swapping a data source doesn't mean rewriting your orchestration.
For the studio, this matters. I run a custom orchestration layer called VERA that coordinates agents across products. MCP lets me plug different context servers into different agents without touching the core loop. A research agent can pull from one set of MCP servers. A content pipeline agent pulls from another. The model doesn't care — it just sees tools.
OpenAI: Agents SDK with Built-In Primitives
OpenAI's Agents SDK (formerly the Assistants API, now substantially rebuilt) gives you higher-level primitives out of the box: agents, handoffs, guardrails, and tracing. The SDK handles the loop. You define agents declaratively, wire in tools, and the framework manages execution state.
The upside is speed to first working agent. The primitives are ergonomic. Handoffs between agents — where one agent delegates to a specialist — are first-class. The tracing built into the SDK makes debugging a multi-agent flow significantly less painful than rolling your own logging.
The tradeoff is control. When the framework manages the loop, you're working within its assumptions about how agents should behave. For simple flows, that's fine. For complex, stateful, multi-product orchestration, you start fighting the framework eventually.
---

